A 306-bed acute care hospital, Penn State Health Holy Spirit Medical Center serves the greater Harrisburg region with outpatient and inpatient diagnostic, medical and surgical services on its East Pennsboro Township, Pa., campus and outpatient locations in Cumberland, Dauphin, Perry and Northern York counties. The four-story Ortenzio Heart Center at Penn State Health Holy Spirit Medical Center is devoted to the care and treatment of patients with heart problems. Its level II trauma center physicians and staff provide around-the-clock complex critical care for those suffering from life-threatening injuries.

Holy Spirit Medical Center has earned national accreditations for its centers of excellence in the treatment of cardiac care, atrial fibrillation, heart attack, heart failure, stroke, diabetes, knee and hip replacement, spine surgery, bariatric surgery, and maternity care. Holy Spirit was founded in 1963 and joined Penn State Health in 2020.

Penn State Health Holy Spirit Medical Center is a community Catholic hospital sponsored by the Sisters of Christian Charity to carry out the healing ministry of Jesus Christ to all in need. The nursing team provides patient care in a supportive, caring, compassionate environment where all clinical and non-clinical staff work together to achieve the patient's best outcome. We provide quality driven, ethically guided, cost-effective and patient-focused health care services to develop healthy communities in the greater Harrisburg area and south-central Pennsylvania.

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