Inherited Neuropathies and CMT
Inherited diseases of the nervous system affect 1 in 2,500 people in the United States. Charcot-Marie-Tooth disease (CMT) is the most common inherited neuropathy. Inherited neuropathies cause damage to the nerves that control your muscles, most commonly in the feet and hands. It affects both your motor and sensory nerves so you may lose the sense of heat, cold and pain.
Charcot Marie Tooth Disease Symptoms, Diagnosis, Treatment
Symptoms
Symptoms of CMT vary in everyone and usually start to appear when you are a young adult.
Common symptoms include:
- Difficulty lifting your foot
- Foot deformities, including a high arch and bent toes
- Loss of muscle in hands and feet
- Numbness, tingling, burning, or loss of sensation in your hands and feet
- Pain in your hands and feet
- Weakness in muscles of your foot and lower leg
Diagnosis
The experts at Penn State Health start with a thorough physical exam and medical history by a neurologist (nervous system doctor). Other testing may include:
- Nerve conduction velocity (NCV) – electoral test to assess nerve impulses and detect nerve injury
- Electromyography (EMG) – assesses muscle and motor nerve cell health
- Genetic testing
- Bloodwork
- Nerve biopsy
Services and Treatments
There is no cure for CMT, but treatments can help you manage the symptoms and improve your quality of life. Treatments may include:
- Lifestyle modifications (exercise and diet)
- Medication
- Occupational therapy
- Orthopedic devices (braces, splints)
- Physical therapy
Experts in Care
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Find a doctor near youWhy Choose Penn State Health for Care
We understand that Charcot-Marie-Tooth (CMT) disease is a chronic condition that affects many aspects of daily life. Our team is committed to providing compassionate, comprehensive care tailored to each patient and family.
The Charcot-Marie-Tooth Association (CMTA) has recognized Penn State Health Milton S. Hershey Medical Center as a Center of Excellence for CMT care. This designation reflects our dedication to delivering high-quality, specialized treatment for individuals living with CMT.
Our multidisciplinary clinic brings together neuromuscular neurologists, physical therapists, occupational therapists, and social workers who work collaboratively to support patients at every stage of their journey. We focus not only on medical management, but also on improving mobility, function, and overall quality of life.
In addition, we connect patients and families with other available services and community resources whenever needed, ensuring they have the support and guidance necessary to navigate life with CMT.
Support Groups
Support groups provide an opportunity to share your feelings and connect with other patients and caregivers who are experiencing similar struggles.
Convenient Locations
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