Nelson Shu-Sang S. Yee, MDPhD, RPh

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Nelson Shu-Sang S. Yee, MDPhD,  RPh
Employed by Penn State Health
Medical Oncology

Academic Appointments

Associate Professor of Medicine
Team Leader, Gastrointestinal Oncology

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About Me

Dr. Nelson S. Yee is the team leader of gastrointestinal oncology at Penn State Cancer Institute and Penn State Health Milton S. Hershey Medical Center and an associate professor of medicine at Penn State College of Medicine. As a board-certified medical oncologist, Dr. Yee specializes in diagnosing and treating patients with cancer in various digestive organs, including the pancreas, biliary tract, liver, and gastrointestinal tract and colon.

As the principal investigator of clinical studies targeting malignant diseases of the digestive system, Dr. Yee develops new therapies, predictive biomarkers, and therapeutic targets. He has published numerous research articles, reviews, case reports, editorials, commentaries and book chapters and presented at research conferences in China, Hong Kong, Macao, Germany and the U.S. Additionally, he is an invited reviewer of grant applications for funding organizations around the globe.

After completing dual Bachelor of Science degrees in pharmacy and chemistry at Massachusetts College of Pharmacy, Dr. Yee earned Doctor of Medicine and Doctor of Philosophy degrees at Weill Cornell Medical College and Memorial Sloan Kettering Cancer Center. At Hospital of University of Pennsylvania, he pursued clinical training in internal medicine, hematology and medical oncology. Before joining Penn State College of Medicine, Dr. Yee taught medicine at University of Pennsylvania and University of Iowa. 


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Professional Education


Medical School, Cornell University Medical College (New York) - 1995


Fellowship, Hematology/Oncology Hospital of the University of Pennsylvania (Penn Medicine) - 2001


Residency, Internal Medicine Hospital of the University of Pennsylvania (Penn Medicine) - 1998


Internship, Internal Medicine Hospital of the University of Pennsylvania (Penn Medicine) - 1996

Research Interests

  • Clinical Evaluation of Cancer Biomarkers and Targets in Digestive Organs
  • Clinical Trials of Therapy in Cancer of Digestive Organs

Academic Interests

  • Academic Editor, Disease Markers
  • Associate Editor, Frontiers in Oncology
  • Associate Editor, Molecular and Cellular Oncology
  • Course Director, Acting Internship in Hematology/Oncology
  • Course Director, Career Exploration and Synthesis in Hematology/Oncology
  • Course Director, Clinical Elective in Hematology
  • Course Director, Clinical Elective in Medical Oncology
  • Course Director, Medicine Clerkship in Hematology/Oncology
  • Editor-in-Chief, World Journal of Translational Medicine
  • Faculty Coordinator, Ambulatory rotation in Hematology/Oncology for Medical Residents
  • Guest Editor, Biomedicines
  • Guest Editor, Clinical Cancer Drugs
  • Guest Editor, Current Clinical Pharmacology
  • Lead Guest Editor, Cancer Growth and Metastasis
  • Regional Editor, Clinical Cancer Drugs
  • Regional Editor, Current Molecular Pharmacology
  • Section Editor, Applied Clinical Research, Clinical Trials and Regulatory Affairs
  • Section Editor, Journal of Clinical Medicine


  • American Cancer Society Alvan T.- and Viola D. Fuller Jr. Research Fellowship, Dana-Farber Cancer Institute
  • American Cancer Society Institutional Research grant, University of Iowa
  • Diplomate in Internal Medicine, American Board of Internal Medicine
  • Diplomate in Medical Oncology, American Board of Internal Medicine
  • Doctor of Philosophy (Molecular Biology), Cornell University Graduate School of Medical Sciences and Memorial Sloan-Kettering Cancer Center
  • Dual Bachelor of Science (Pharmacy and Chemistry), Summa Cum Laude, Valedictorian, Massachusetts College of Pharmacy
  • Eli Lilly Achievement Award
  • Medical Scientist Training Program Fellowship, Robert Wood Johnson, Jr. Charitable Trust
  • Mentored Clinical Scientist Career Development Award, National Institutes of Health
  • Rho Chi, The Academic Honor Society in Pharmacy
  • The William Osler Society of Fellows in Medicine, University of Pennsylvania