Nelson Shu-Sang S. Yee, MD, PhD, RPh

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Nelson Shu-Sang S. Yee, MD, PhD, RPh
Hematology, Hematology & Oncology, Medical Oncology

Academic Appointments

Associate Professor of Medicine
Team Leader, Gastrointestinal Oncology

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About Me

Dr. Nelson S. Yee is the team leader of gastrointestinal oncology at Penn State Cancer Institute and Penn State Health Milton S. Hershey Medical Center and an associate professor of medicine at Penn State College of Medicine. As a board-certified medical oncologist, Dr. Yee specializes in diagnosing and treating patients with cancer in various digestive organs, including the pancreas, biliary tract, liver, and gastrointestinal tract and colon.

As the principal investigator of clinical studies targeting malignant diseases of the digestive system, Dr. Yee develops new therapies, predictive biomarkers, and therapeutic targets. He has published numerous research articles, reviews, case reports, editorials, commentaries and book chapters and presented at research conferences in China, Hong Kong, Macao, Germany and the U.S. Additionally, he is an invited reviewer of grant applications for funding organizations around the globe.

After completing dual Bachelor of Science degrees in pharmacy and chemistry at Massachusetts College of Pharmacy, Dr. Yee earned Doctor of Medicine and Doctor of Philosophy degrees at Weill Cornell Medical College and Memorial Sloan Kettering Cancer Center. At Hospital of University of Pennsylvania, he pursued clinical training in internal medicine, hematology and medical oncology. Before joining Penn State College of Medicine, Dr. Yee taught medicine at University of Pennsylvania and University of Iowa. 

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Professional Education


Medical School, Cornell University Medical College (New York) - 1995


Fellowship, Hematology/Oncology Hospital of the University of Pennsylvania (Penn Medicine) - 2001


Internship, Internal Medicine Hospital of the University of Pennsylvania (Penn Medicine) - 1996

Residency, Internal Medicine Hospital of the University of Pennsylvania (Penn Medicine) - 1998

Research Interests

  • Clinical Evaluation of Cancer Biomarkers and Targets in Digestive Organs
  • Clinical Trials of Therapy in Cancer of Digestive Organs

Academic Interests

  • Course Director, Clinical Elective in Hematology
  • Regional Editor, Clinical Cancer Drugs
  • Associate Editor, Frontiers in Oncology
  • Section Editor, Journal of Clinical Medicine
  • Editor-in-Chief, World Journal of Translational Medicine
  • Course Director, Acting Internship in Hematology/Oncology
  • Course Director, Medicine Clerkship in Hematology/Oncology
  • Regional Editor, Current Molecular Pharmacology
  • Lead Guest Editor, Cancer Growth and Metastasis
  • Guest Editor, Biomedicines
  • Faculty Coordinator, Ambulatory rotation in Hematology/Oncology for Medical Residents
  • Academic Editor, Disease Markers
  • Course Director, Clinical Elective in Medical Oncology
  • Course Director, Career Exploration and Synthesis in Hematology/Oncology
  • Guest Editor, Current Clinical Pharmacology
  • Section Editor, Applied Clinical Research, Clinical Trials and Regulatory Affairs
  • Guest Editor, Clinical Cancer Drugs
  • Associate Editor, Molecular and Cellular Oncology


  • Diplomate in Internal Medicine, American Board of Internal Medicine
  • The William Osler Society of Fellows in Medicine, University of Pennsylvania
  • Dual Bachelor of Science (Pharmacy and Chemistry), Summa Cum Laude, Valedictorian, Massachusetts College of Pharmacy
  • American Cancer Society Alvan T.- and Viola D. Fuller Jr. Research Fellowship, Dana-Farber Cancer Institute
  • Rho Chi, The Academic Honor Society in Pharmacy
  • Eli Lilly Achievement Award
  • American Cancer Society Institutional Research grant, University of Iowa
  • Doctor of Philosophy (Molecular Biology), Cornell University Graduate School of Medical Sciences and Memorial Sloan-Kettering Cancer Center
  • Medical Scientist Training Program Fellowship, Robert Wood Johnson, Jr. Charitable Trust
  • Diplomate in Medical Oncology, American Board of Internal Medicine
  • Mentored Clinical Scientist Career Development Award, National Institutes of Health