Specimen Tube Type Transport
Urine Container with no preservatives
Summary Test Name
Benzodiazepines, Urine
Specimen Preparation Outreach
Refrigerate until courier pickup
Specimen Stability
5 days refrigerated
Minimum Volume
10 ml in urine container
Specimen Transport
Refrigerate
Stat Availability
24 hours a day, seven days a week
Test Turnaround Time Routines And Stats
R 4 hours S 2 hours
Reference Value
None Detected
Additional Test Information
ASSAY CUTOFF: ≥300 ng/mL
ANALYTICAL SPECIFICITY:
|
|
Compound(d)
|
ng/mL
Equivalent to
300 ng/mL
cutoff
|
Approx.
%
Cross-reactivity
|
|
Bromazepam
|
229
|
131
|
|
3-Hydroxybromazepam
|
504
|
59
|
|
Demoxepam
|
256
|
117
|
|
Deschloretizolam
|
257
|
117
|
|
Estazolam
|
270
|
111
|
|
Diazepam
|
273
|
110
|
|
Nordiazepam
|
305
|
98
|
|
Temazepam
|
272
|
110
|
|
Temazepam glucuronide
|
496
|
61
|
|
Alprazolam
|
275
|
109
|
|
4-Hydroxyalprazolam
|
192
|
156
|
|
α-Hydroxyalprazolam
|
275
|
109
|
|
α-Hydroxyalprazolam glucuronide
|
567
|
53
|
|
Oxazepam
|
275
|
109
|
|
Oxazepam glucuronide
|
442
|
68
|
|
Clobazam
|
277
|
108
|
|
Nitrazepam
|
294
|
102
|
|
7-Aminonitrazepam
|
230
|
131
|
|
7-Acetamidonitrazepam
|
93148
|
0.3
|
|
Nimetazepam
|
309
|
97
|
|
7-Aminonimetazepam
|
283
|
106
|
|
Pyrazolam
|
311
|
96
|
|
Clonazepam
|
317
|
95
|
|
7-Aminoclonazepam
|
390
|
77
|
|
Diclazepam
|
317
|
95
|
|
Triazolam
|
315
|
95
|
|
α-Hydroxytriazolam
|
312
|
96
|
|
4-Hydroxytriazolam
|
319
|
94
|
|
Lorazepam
|
323
|
93
|
|
Lorazepam glucuronide
|
519
|
58
|
|
Flubromazolam
|
327
|
92
|
|
Lormetazepam
|
328
|
92
|
|
Pinazepam
|
327
|
92
|
|
Flunitrazepam
|
329
|
91
|
|
Desmethylflunitrazepam
|
301
|
100
|
|
7-Aminoflunitrazepam
|
343
|
87
|
|
3-Hydroxyflunitrazepam
|
399
|
75
|
|
Delorazepam
|
334
|
90
|
|
Midazolam
|
332
|
90
|
|
α-Hydroxymidazolam
|
326
|
92
|
|
α-Hydroxymidazolam glucuronide
|
569
|
53
|
|
Clonazolam
|
338
|
89
|
|
Etizolam
|
362
|
83
|
|
Prazepam
|
363
|
83
|
|
Tetrazepam
|
360
|
83
|
|
Chlordiazepoxide
|
374
|
80
|
|
Desmethylchlordiazepoxide
|
370
|
81
|
|
Phenazepam
|
382
|
78
|
|
Bentazepam
|
393
|
76
|
|
Medazepam
|
394
|
76
|
|
Desmethylmedazepam
|
549
|
55
|
|
Brotiazolam
|
407
|
74
|
|
Halazepam
|
406
|
74
|
|
Meclonazepam
|
409
|
73
|
|
Nifoxipam
|
412
|
73
|
|
Flubromazepam
|
435
|
69
|
|
3-Hydroxyflubromazepam
|
401
|
75
|
|
Flurazepam
|
487
|
62
|
|
Desalkylflurazepam
|
307
|
98
|
|
Hydroxyethylflurazepam
|
324
|
92
|
|
Didesethylflurazepam
|
352
|
85
|
|
Clorazepate
|
601
|
50
|
|
Many benzodiazepines appear in the urine largely as the glucuronidated conjugate. Glucuronidated metabolites may have more or less cross-reactivity than the parent compound.
